When?
4-5 April 2019

Where?

Organisers:
RSBI (@RoBioinfo) and Faculty of Biology, Alexandru Ioan Cuza University of Iași

Aim: The workshop is aimed at master and PhD students as well as young researchers working with protein sequences and structures. Several core bioinformatics techniques of sequence similarity searching as well as the UniProt database will be discussed. The workshop will also provide hands-on experience of exploring and analyzing the 3D macromolecular structure data available in the Protein Data Bank (PDB).

Requirements: Basic (undergrad level) understanding of Molecular Biology and Protein structure is a must. No prior experience of bioinformatics is required.
Speakers: TBA
Schedule: TBD, as a draft:

Day 1.

Time Subject Trainer/Speaker
9:00 – 9:30 Welcome note and coffee Organisers
9:30 – 11:00 (hands on) Introduction to programming. Usefull commands in Unix shell and Python Claudiu Mihăilă
11:00 – 11:30 Coffee break
11:30 – 12:30 Sequence searching and alignments. Basic introduction in sequence similarity searching and sequence homology (DNA/RNA vs proteins sequences) (Part I) TBD
12:30 – 13:30 Lunch
13:30 – 15:00 Sequence searching and alignments. Basic introduction in sequence similarity searching and sequence homology (DNA/RNA vs proteins sequences)(Part II) TBD
15:00 – 15:30 Talk TBD
15:30 – 16:00 Coffee Break
16:00 – 18:00 Protein sequence and Function (UniProt, Gene Ontology) – UniProt database to identify information about all aspects of a protein of interest. TBD
19:00 Festive dinner

Day 2.

Time Subject Trainer/Speaker
9:30 – 10:30 (hands on) Introduction to programming. Programmatic access of public databases and data retrieval Claudiu Mihăilă
10:30 – 11:00 Coffee Break
11:00 – 12:30 Introduction to macromolecular structure at the PDBe. Retrieve and assess the quality of structural data from the PDB, Visualise and analyse structures TBD
12:030 – 13:30 Lunch
13:30 – 15:00 Analysing macromolecular structures at the PDBe. Assess protein-ligand interactions and analyse binding sites (I) TBD
15:00 – 15:30 Coffee break
15:30 – 15:55 Analysing macromolecular structures at the PDBe. Assess protein-ligand interactions and analyse binding sites (II) TBD
15:55 – 16:20 Talk TBD
16:20 – 17:00 Panel Discussion: AI’s contribution to construct predictions of protein structures. All speakers and trainers
16:45 – 17:00 Farewell
18:30 Beer and science event

Organising committee:
Claudiu Mihăilă (London, UK)
Monica Abrudan (Cambridge, UK)
Bogdan Mirăuță (Cambridge, UK)
Marius Mihășan (Iași, Romania)

Sponsors:
bioactive.bio.uaic
http://www.bio.uaic.ro/cercetare/grupuri/bioactive/index.html

Categories: RSBI Events